Important It is possible that the main title of the report Narcolepsy is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
narcolepsy with cataplexy
narcolepsy without cataplexy
Narcolepsy is a neurological sleep disorder characterized by chronic, excessive attacks of drowsiness during the day, sometimes called excessive daytime sleepiness (EDS). Attacks of drowsiness may persist for only a few seconds or several minutes. These episodes vary in frequency from a few incidents to several during a single day. Nighttime (nocturnal) sleep patterns may also be disrupted. Three additional symptoms often associated with narcolepsy are sudden extreme muscle weakness (cataplexy), a specific type of hallucination that occurs just before falling asleep or upon awakening, and brief episodes of paralysis while waking up. The exact incidence of narcolepsy is 1 in 2,000 and most researchers believe that the disorder remains undiagnosed or misdiagnosed in many cases.
There is increasing evidence that narcolepsy is an autoimmune disorder. Autoimmune disorders are caused when the body's immune system mistakenly attacks healthy tissue or cells. In narcolepsy, the immune system destroys certain brain cells that produce a peptide called hypocretin. Why the immune system attacks healthy cells in narcolepsy is unknown and additional environmental and genetic factors may play a role in the development of the disorder.
National Sleep Foundation 1010 N. Glebe Road Suite 310 Arlington, VA 22201 Tel: (703)243-1697 Email: firstname.lastname@example.org Internet: http://www.sleepfoundation.org
Narcolepsy Network, Inc. 110 Ripple Lane North Kingstown, RI 02852 USA Tel: (401)667-2523 Fax: (401)633-6567 Tel: (888)292-6522 Email: email@example.com Internet: http://www.narcolepsynetwork.org
American Sleep Association 1610 14th Street NW Suite 300 Rochester, MN 55901 Tel: (507)287-6006 Fax: (507)287-6008 Email: firstname.lastname@example.org Internet: http://www.sleepassociation.org/
Narcolepsy Institute Montefiore Medical Center 111 East 210th Street Bronx, NY 10467 Tel: (718)920-6799 Fax: (718)654-9580 Email: MGoswami@NarcolepsyInstitute.org Internet: http://www.narcolepsyinstitute.org
NIH/National Institute of Neurological Disorders and Stroke P.O. Box 5801 Bethesda, MD 20824 Tel: (301)496-5751 Fax: (301)402-2186 Tel: (800)352-9424 TDD: (301)468-5981 Email: email@example.com Internet: http://www.ninds.nih.gov/
MedicAlert Foundation International 2323 Colorado Avenue Turlock, CA 95382 USA Tel: (209)669-2401 Fax: (209)669-2456 Tel: (888)633-4298 Email: Inquiries@medicalert.org Internet: http://www.medicalert.org
Center for Narcolepsy, Sleep and Health Research College of Nursing, Suite 208 The University of Illinois at Chicago 845 South Damen Avenue (M/C 802) Chicago, IL 60612 Tel: (312)996-5176 Fax: (312)996-7008 Email: firstname.lastname@example.org Internet: http://www.uic.edu/nursing/CNSHR/index.html
MUMS National Parent-to-Parent Network 150 Custer Court Green Bay, WI 54301-1243 USA Tel: (920)336-5333 Fax: (920)339-0995 Tel: (877)336-5333 Email: email@example.com Internet: http://www.netnet.net/mums/
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
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