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Hydralazine

Topic Contents

Hydralazine

Drug Information

Hydralazine is a drug used to lower blood pressure in people with hypertension . Hydralazine relaxes the muscles that control the diameter of blood vessels. This relaxation allows the blood vessels to dilate (open wider), lowering blood pressure.

Common brand names:

Apresoline

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • Vitamin B6

    Vitamin B6 can bind to hydralazine to form a complex that is excreted in the urine, increasing vitamin B6 loss.1 This may lead to vitamin B6 deficiency.2 People taking hydralazine should consult with their doctor to discuss the possibility of vitamin B6 supplementation.

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • none

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 131–2.

2. Raskin NH, Rishman RA. Pyridoxine-deficiency neuropathy due to hydralazine. N Engl J Med 1965;273:1182–5.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

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