Billings Clinic
Especially For:

Complementary Medicine - Cam

Calcium Acetate

Topic Contents

Calcium Acetate

Drug Information

Calcium acetate is used to prevent high phosphorus blood levels in people with kidney failure.

Common brand names:

Calphron, PhosLo

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • Zinc

    People with renal failure or on hemodialysis often have low blood levels of zinc, which may produce symptoms such as abnormal taste or smell, reduced sexual functions, and poor immunity. One controlled study showed that taking zinc at the same time as calcium acetate reduces absorption of zinc.1 Therefore, people should avoid taking calcium acetate and zinc supplements together. Another controlled study revealed that neither short-term nor long-term treatment with calcium acetate results in reduced blood zinc levels.2 Thus, while calcium acetate reduces the amount of zinc absorbed from supplements, long-term treatment with the drug does not appear to affect overall zinc status. However, people with renal failure who experience symptoms of zinc deficiency might benefit from supplementing with zinc, regardless of whether or not they take calcium acetate.

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • Calcium

    People with kidney failure may develop high blood levels of calcium while taking calcium acetate. Since calcium acetate is a source of supplemental calcium, people taking the drug should avoid taking additional calcium supplements.3 People experiencing adverse effects of high blood calcium—such as loss of appetite, mental depression, poor memory, and muscle weakness—should notify their healthcare practitioner.

  • Magnesium

    Calcium-containing antacids, when taken together with calcium acetate, may result in abnormally high blood levels of calcium.4 Consequently, people taking calcium acetate should avoid taking calcium-containing antacids.

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Hwang SH, Lai YH, Chen HC, Tsai JH. Comparisons of the effects of calcium carbonate and calcium acetate on zinc tolerance test in hemodialysis patients. Am J Kidney Dis 1992;19:57–60

2. Hwang SJ, Chang JM, Lee SC, et al. Short- and long-term uses of calcium acetate do not change hair and serum zinc concentrations in hemodialysis patients. Scand J Clin Lab Invest 1999;59:83–7.

3. Sifton DW, et. Physicians’ Desk Reference. Montvale, NJ: Medical Economics Company, Inc., 2000, 811–2.

4. Sifton DW, et. Physicians’ Desk Reference. Montvale, NJ: Medical Economics Company, Inc., 2000, 811–2.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

Print This Page
Email to a Friend
Home | Contact | Site Map | Site Privacy Policy | Terms & Conditions | Patient Privacy Policy | Medical Records | Fast Command
2800 10th Ave. North | P.O. Box 37000 | Billings, Montana 59107 | 406.238.2500
© Copyright 2014 Billings Clinic. All Rights Reserved.