Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
3 StarsReliable and relatively consistent scientific data showing a substantial health benefit.
2 StarsContradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1 StarFor an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
This supplement has been used in connection with the following health conditions:
Indigestion, Heartburn, and Low Stomach Acidity
Refer to label instructions
Bitter herbs are thought to stimulate digestive function by increasing saliva production and promoting both stomach acid and digestive enzyme production.6 As a result, they are particularly used when there is low stomach acid but not in heartburn (where too much stomach acid could initially exacerbate the situation). These herbs literally taste bitter. Some examples of bitter herbs include greater celandine, wormwood, gentian,dandelion, blessed thistle, yarrow, devil’s claw, bitter orange, bitter melon, juniper, andrographis, prickly ash, and centaury.7. Bitters are generally taken either by mixing 1–3 ml tincture into water and sipping slowly 10–30 minutes before eating, or by making tea, which is also sipped slowly before eating.
Refer to label instructions
Gentian root and other highly bitter plants have been used for centuries by herbalists in Europe as digestive aids (the well-known Swedish bitters often contain gentian). Gentian is still used to treat poor appetite and indigestion.8 An open study shows that gentian tincture inhibits the feeling of fullness after eating, suggesting it could improve poor appetite.9 However, gentian should not be used by people suffering from excessive stomach acid, heartburn, peptic ulcer disease, or gastritis.10
One of the most popular supportive treatments for both acute and chronic sinusitis in Germany is an herbal combination containing gentian root, primrose flowers, sorrel herb, elder flowers, and European vervain.11 The combination has been found to be useful in helping to promote mucus drainage (“mucolytic” action) from the sinuses.12 The combination is typically used together with antibiotics for treating acute sinusitis.
Traditional Use (May Not Be Supported by Scientific Studies)
Gentian root and other highly bitter plants have been used for centuries by herbalists in Europe as digestive aids (the well-known Swedish bitters often contain gentian). Other folk uses included topical application on skin tumors, decreasing fevers, and treatment of diarrhea.1
Active constituents: Gentian contains bitter substances such as the glycosides gentiopicrin and amarogentin. The bitter taste of these can be detected even when diluted 50,000 times.2 Besides stimulating secretion of saliva in the mouth and hydrochloric acid in the stomach, gentiopicrin may protect the liver.3 Gentian is used to treat poor appetite and indigestion.4 An open study shows that gentian tincture inhibits the feeling of fullness after eating, suggesting it could improve poor appetite.5
How It Works
How to Use It
Tincture can be taken 20 minutes before each meal, for a total of 1/4–1/2 teaspoon (1–3 ml) daily. Alternatively, whole root, 1/2–3/4 teaspoon (2–4 grams) per day, can be used. Since capsules of the herb bypass the taste buds, they may not have the same effect as other dosage methods.
Interactions with Supplements, Foods, & Other Compounds
At the time of writing, there were no well-known supplement or food interactions with this supplement.
Interactions with Medicines
As of the last update, we found no reported interactions between this supplement and medicines. It is possible that unknown interactions exist. If you take medication, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.
At the time of writing, there were no well-known side effects caused by this supplement.
7. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 425–6.
The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2014.
How this information was developed to help you make better health decisions.
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