Complementary Medicine - Cam
Parts Used & Where Grown
The tea tree grows in Australia and Asia. This tall evergreen tree has a white, spongy bark. The oil from the leaves is used medicinally.
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Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
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3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2 Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
This supplement has been used in connection with the following health conditions:
Traditional Use (May Not Be Supported by Scientific Studies)
Australian Aborigines used the leaves to treat cuts and skin infections. They would crush the leaves and apply them to the affected area. Captain James Cook and his crew named the tree “tea tree,” using its leaves as a substitute for tea as well as to flavor beer. Australian soldiers participating in World War I were given tea tree oil as a disinfectant, leading to a high demand for its production.
How It Works
How It Works
The oil contains numerous chemicals known as terpenoids. Australian standards were established for the amount of one particular compound, terpinen-4-ol, which must make up at least 30% and preferably 40–50% of the oil for it to be medically useful. Another compound, cineole, should make up less than 15% and preferably 2.5% of the oil. The oil kills fungus and bacteria, including those resistant to some antibiotics.15 , 16 For common acne , a double-blind trial compared the topical use of 5% tea tree oil to 5% benzoyl peroxide.17 Although the tea tree oil was slower and less potent in its action, it had far fewer side effects and was thus considered more effective overall.
A double-blind trial found that a 10% tea tree oil cream was as effective as anti-fungal medicine at improving symptoms associated with athlete’s foot , though it was not more effective than a placebo for eliminating the fungal infection.18 A double-blind trial found 100% tea tree oil applied topically was as effective as the anti-fungal medicine clotrimazole (Lotrimin®, Mycelex®) for people with fungus affecting the toe nails, a condition known as onychomycosis.19 In another double-blind trial with toenail fungus sufferers, a combination of 5% tea tree oil and 2% butenafine (Mentax®), a synthetic anti-fungal drug, in a cream proved more effective than an unspecified concentration of tea tree oil in cream alone.20 The results are not entirely surprising, as the tea tree product alone was probably not at a sufficiently high enough concentration to be effective.
A preliminary trial found that rinsing the mouth with 1 tablespoon (15 ml) tea tree oil solution four times daily effectively treated thrush (oral yeast infections) in AIDS patients.21 Solutions containing no more than 5% should be used orally and should never be swallowed.
A concern for hospital staff and patients is the spread of the bacteria Staphylococcus aureus—sometimes referred to as a “staph infection.” One small clinical trial found that use of a 4% tea tree oil nasal ointment as well as a 5% tea tree oil body wash was slightly more effective than standard drugs used to prevent the spread of the bacteria.22
How to Use It
Oil at a strength of 70–100% should be applied moderately at least twice per day to the affected areas of skin or nail.23 For topical treatment of acne , the oil is used at a dilution of 5–15%. Concentrations as strong as 40% may be used—with extreme caution and qualified advice—as vaginal douches. For thrush in immune-compromised adults, tea tree oil diluted to 5% or less is used in the amount of 1 tablespoon (15 ml) four times daily (as a mouth rinse). Tea tree oil should never be swallowed.
Interactions with Supplements, Foods, & Other Compounds
At the time of writing, there were no well-known supplement or food interactions with this supplement.
Interactions with Medicines
As of the last update, we found no reported interactions between this supplement and medicines. It is possible that unknown interactions exist. If you take medication, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.
While tea tree oil can be applied to minor cuts and scrapes, use caution for more extensive areas of broken skin or areas affected by rashes not due to fungus. The oil may burn if it gets into the eyes, nose, mouth, or other tender areas. Some people have allergic reactions, including rashes and itching, when applying tea tree oil.24 For this reason, only a small amount should be applied when first using it.
In case reports, three young boys developed breast enlargement (gynecomastia) after repeated topical application of products that contained lavender oil and tea tree oil. The problem resolved after they stopped using the oils. While a cause–effect relationship was not conclusively proven, it was suggested by the fact that these oils have been found to have estrogen-like effects in test tube studies.25 Tea tree oil should never be swallowed, as it may cause nerve damage and other problems.
1. Enshaieh S, Jooya A, Siadat AH, Iraji F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian J Dermatol Venereol Leprol 2007;73:22–5.
2. Tong MM, Altman PM, Barnetson RS. Tea tree oil in the treatment of tinea pedis. Aust J Dermatol 1992;33:145–9.
3. Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033–7.
4. Kato T, Iijima H, Ishihara K, et al. Antibacterial effects of Listerine on oral bacteria. Bull Tokyo Dent Coll 1990;31:301–7.
5. Cosentino S, Tuberoso CI, Pisano B, et al. In-vitro antimicrobial activity and chemical composition of Sardinian Thymus essential oils. Lett Appl Microbiol 1999;29:130–5.
6. Petersson LG, Edwardsson S, Arends J. Antimicrobial effect of a dental varnish, in vitro. Swed Dent J 1992;16:183–9.
7. Cox SD, Mann CM, Markham JL, et al. The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil). J Appl Microbiol 2000;88:170–5.
8. Serfaty R, Itic J. Comparative trial with natural herbal mouthwash versus chlorhexidine in gingivitis. J Clin Dent 1988;1:A34–7.
9. Dolara P, Corte B, Ghelardini C, et al. Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh. Planta Med 2000;66:356–8.
10. Hannah JJ, Johnson JD, Kuftinec MM. Long-term clinical evaluation of toothpaste and oral rinse containing sanguinaria extract in controlling plaque, gingival inflammation, and sulcular bleeding during orthodontic treatment. Am J Orthod Dentofacial Orthop 1989;96:199–207.
11. Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033–7.
12. Pena E. Melaleuca alternifolia oil: Its use for trichomonal vaginitis and other vaginal infections. Obstet Gynecol 1962;19:793–5.
13. Carson CF, Riley TV. Antimicrobial activity of the essential oil of Melaleuca alternifolia: A review. Lett Appl Microbiol 1993;16:49–55.
14. Faoagali J, George N, Leditschke JF. Does tea tree oil have a place in the topical treatment of burns? Burns 1997;23:349–51.
15. Carson CF, Riley TV. Antimicrobial activity of the essential oil of Melaleuca alternifolia—A review. Lett Appl Microbiol 1993;16:49–55.
16. Carson CF, Cookson BD, Farrelly HD, Riley T. Susceptibility of methicillin-resistant Staphylococcus aureus to the essential oil of Melaleuca alternifolia. J Antimicrobial Chemother 1995;35:421–4.
17. Bassett IB, Pannowitz DL, Barnetson RS. A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med J Austral 1990;153:455–8.
18. Tong MM, Altman PM, Barnetson RS. Tea tree oil in the treatment of tinea pedis. Austral J Dermatol 1992;33:145–9.
19. Buck DS, Nidorf DM, Addino JG. Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole. J Garm Pract 1994;38:601–5.
20. Syed TA, Qureshi ZA, Ali SM, et al. Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream. Trop Med Intl Health 1999;4:284–7.
21. Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033–7.
22. Caelli M, Porteous J, Carson CF, et al. Tea tree oil as an alternative topical decolonization agent for methicillin-resistant Staphylococcus aureus. J Hospital Infect 2000;46:236–7.
23. Brown DJ. Phytotherapeutic approaches to common dermatological conditions. Quart Rev Natural Med 1998;Summer:161–73.
24. Knight TE, Hansen BM. Melaleuca oil (tea tree oil) dermatitis. Med J Australia 1994;30:423–7.
25. Henley DV, Lipson N, Korach KS, Bloch CA. Prepubertal gynecomastia linked to lavender and tea tree oils. N Engl J Med 2007;356:479–85.
Last Review: 02-05-2013
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2014.
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