Prerenal acute renal failure is the most common type of acute renal
failure, accounting for about 55 out of 100 acute renal failure cases.1 It can be a complication of almost any disease, condition, or
medicine that causes a decrease in the normal amount of blood and fluid in
Causes of prerenal acute renal failure include:
Severe blood loss and low blood pressure related
to major cardiac or abdominal surgery, severe infection (sepsis), or injury.
interfere with the blood supply to the kidneys. Medicines such as ACE inhibitors and common pain medicines (NSAIDs) commonly cause
prerenal acute renal failure in people who already have an increased risk for
Treatment focuses on correcting the cause of the prerenal acute renal
failure. Depending on the cause, the condition often reverses itself within a
couple of days after normal blood flow to the kidneys has been restored.
But if it is not reversed or treated successfully and quickly, prerenal
acute renal failure can cause tissue death in the kidneys and lead to intrinsic
(intrarenal) acute renal failure.
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