Important It is possible that the main title of the report Walker Warburg Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Walker-Warburg syndrome (WWS) is a rare genetic multisystem disorder characterized by muscle disease and brain and eye abnormalities. The specific symptoms and severity of WWS vary greatly from case to case. The most consistent features are a smooth appearance of the surface of the brain due to lack of normal folds (lissencephaly), malformations of other brain structures (cerebellum and brain stem), various developmental abnormalities of the eyes, and progressive degeneration and weakness of the voluntary muscles (congenital muscular dystrophy). WWS is inherited as an autosomal recessive trait.
WWS is considered a form of muscular dystrophy, which is a group of disorders characterized by weakness and atrophy of various voluntary muscles of the body. Approximately 30 different disorders make up the muscular dystrophies. The disorders affect different muscles and have different ages of onset, severity and inheritance patterns.
National Hydrocephalus Foundation 12413 Centralia Rd. Lakewood, CA 90715-1653 USA Tel: (562)924-6666 Fax: (562)924-6666 Tel: (888)857-3434 Email: firstname.lastname@example.org Internet: http://www.nhfonline.org
Guardians of Hydrocephalus Research Foundation 2618 Avenue Z Brooklyn, NY 11235 Tel: (718)743-4473 Fax: (718)743-1171 Tel: (800)458-8655 Email: email@example.com Internet: http://www.ghrforg.org/
Hydrocephalus Association 870 Market Street Suite 955 San Francisco, CA 94102 USA Tel: (415)732-7040 Fax: (415)732-7044 Tel: (888)598-3789 Email: firstname.lastname@example.org Internet: http://www.hydroassoc.org
NIH/National Institute of Neurological Disorders and Stroke P.O. Box 5801 Bethesda, MD 20824 Tel: (301)496-5751 Fax: (301)402-2186 Tel: (800)352-9424 TDD: (301)468-5981 Email: email@example.com Internet: http://www.ninds.nih.gov/
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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Last Updated: 3/10/2009 Copyright 1993, 1995, 1996, 1999, 2007, 2009 National Organization for Rare Disorders, Inc.
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