"A Randomized Phase II Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases."
The Hippocampus is an important structure in the brain for memory. Doctors hope avoiding the hippocampus will prevent memory loss and deterioration of thinking ability after whole-brain radiotherapy, although there is no proof of this yet. In this study you get whole-brain radiotherapy while the hippocampus is shielded from high doses of radiation.
Evidence of brain metastasis with a gadolinium contrast enhanced MRI. No history of prior small cell lung cancer and/or germ cell malignancy.